man, both of you, bunky and jared, are saying good stuff. i still can't quite wrap my head around the 'physics' of it (bunky you're exactly right the "lever" is the same; the contact point with rear tire up to axle is key... so why should circumference of wheel matter?? but somehow it feels like it does??? ) . i've ridden my buddy Vernon's InDust 2Ton 22" bike with a 14"cs
http://www.plussizebmx.com/blog/2011/11/7/bike-check-indust-2-ton-22.html and it does not feel as quick as a 20" wheel bike with 14"cs. yes it's quick, but not thaaaat quick. i'll have to go out and experiment again on my different bikes tomorrow. jared, you're definitely right, sometimes "locking in" to manuals is more important--(look at bmx race bikes with long cs's for high-speed and over-roller manuals or mtbmx26"s with minimal bb drop and short cs's....) in the meantime:
i added this little triangle in photoshop to illustrate manual balance points for some how-to thread a while back ... i can't quite put my finger on it, but with my experience with bigger wheeled bikes (22, 24, 26), i feel like there's still a 'wheel effect.'
and for big wheel + short mtb chainstay (like 15-15.5) + small bb drop perspective witness this:
http://www.youtube.com/watch?v=RoWpqzabhpc